NEW REG Publication

Posted September 25, 2025

New REG Publication - Expert Perspectives on Next Generation Health Guidelines: How to Integrate RWE in EBM

NEW REG Publication

Expert Perspectives on Next Generation Health Guidelines: How to Integrate RWE in EBM

We are delighted to share our latest publication, “Expert Perspectives on Next Generation Health Guidelines: How to Integrate RWE in EBM" is now available in the Pragmatic and Observational Research journal.

Real-world evidence (RWE) can supplement randomised controlled trials (RCTs) to improve evidence-based medicine (EBM) and clinical guidelines. Insights from the 2nd EAACI/REG Workshop emphasise the importance of standardised methods, education on RWE, and collaboration with patients and regulators. Practical frameworks are suggested to develop and incorporate high-quality RWE into healthcare decision-making, especially for airway diseases.

As the Expert Group noted,  the integration of Real-World Evidence into evidence-based decision-making has become a practical necessity rather than just a theoretical concept. The workshop consensus highlights that high-quality RWE, when generated and interpreted with rigorous methods, can effectively supplement or sometimes replace data from randomised controlled trials.

https://doi.org/10.1089/jamp.2024.0060